Silencing of the lncRNA TUG1 attenuates epithelial-mesenchymal transition of renal tubular epithelial cells by sponging miR-141-3p via regulating β-catenin.

In conclusion, TUG1 promotes EMT in TGF-β1-induced HK-2 cells by upregulating β-catenin levels through sponging miR-141-3p, suggesting a novel therapeutic candidate for RIF. PMID: 33135476 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/33135476?dopt=Abstract

Source: Am J Physiol Renal P... - November 2, 2020 Category: Urology & Nephrology Authors: Zhang B, Zhao C, Hou L, Wu Y Tags: Am J Physiol Renal Physiol Source Type: research

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