Effects of Gasdermin D in Modulating Murine Lupus and its Associated Organ Damage

ConclusionGSDMD negatively regulates autoantigen generation and immune dysregulation in response to tissue injury and may play previously unappreciated protective roles in systemic autoimmunity.

Source: Arthritis and Rheumatology - October 17, 2020 Category: Rheumatology Authors: Xinghao Wang, Luz P. Blanco, Carmelo Carmona ‐Rivera, Shuichiro Nakabo, Hege L. Pedersen, Zu‐Xi Yu, Mariana J. Kaplan Tags: Full Length Source Type: research