Association between Low-Density Lipoprotein Cholesterol Levels and Proximal Single Subcortical Infarction in Comparison with Distal Single Subcortical Infarction

Single subcortical infarction (SSI) is one of the neuroimaging manifestations of cerebral small vessel disease (CSVD).1,2 According to the reports by Fisher and Caplan during 1960s to 1980s,3 –6 it has been classified into two pathological subtypes in the territory of penetrating arteries, either microatheroma or lipohyalinosis. Microatheroma, which usually affects the proximal segment of penetrating arteries with a diameter of 200 to 400 μm, containing fatty macrophages or foam-cell s in autopsy.
Source: Journal of Stroke and Cerebrovascular Diseases - Category: Neurology Authors: Source Type: research