Association between types of Modic changes in the lumbar region and low back pain in a large cohort: the Wakayama spine study

AbstractPurposeThe clinical significance of Modic changes in low back pain (LBP) is yet to be clarified. Thus, this study aimed to examine the association between Modic changes and LBP after adjustment for confounding factors.MethodsWe evaluated participants in the second Wakayama Spine Study. The degree of endplate changes as measured using magnetic resonance imaging was classified based on the Modic classification system. The prevalence of the types of Modic change in the lumbar region and at each level was assessed. Multivariate logistic regression analysis was conducted to determine the association between the types of Modic changes and LBP with adjustment for age, sex, body mass index, disc degeneration score, and disc displacement score. The LBP intensity was also compared according to the Visual Analogue Scale (VAS) score among the three types of Modic change.ResultsOverall, 814 subjects were evaluated. Type II Modic changes were the most prevalent (41.9%). Only type I Modic changes were significantly associated with LBP (odds ratio): 1.84, 95% confidence interval [CI]: 1.1 –2.9). The LBP VAS score was significantly higher in subjects with type I Modic change than that in those with no Modic change (23.9 ± 26.3 vs. 9.9 ± 19.4,p 
Source: European Spine Journal - Category: Orthopaedics Source Type: research

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Source: Spine - Category: Orthopaedics Tags: RANDOMIZED TRIAL Source Type: research
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Source: Journal of General Internal Medicine - Category: Internal Medicine Source Type: research
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Source: Asian Spine Journal - Category: Orthopaedics Tags: Asian Spine J Source Type: research
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Source: Medicine - Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
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Source: Clinical Radiology - Category: Radiology Authors: Tags: Pictorial Review Source Type: research
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Source: Spine - Category: Orthopaedics Tags: EPIDEMIOLOGY Source Type: research
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Source: Quality of Life Research - Category: Health Management Source Type: research
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Source: Asian Spine Journal - Category: Orthopaedics Tags: Asian Spine J Source Type: research
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