GSE159104 Biomarker Discovery in Attention Deficit Hyperactivity Disorder: RNA sequencing of Whole Blood in Discordant Twin and Case-Controlled Cohorts
Contributors : Joel T Nigg ; Tim McCaffrey ; Georges St.Laurent ; Daniel Jones ; Dmitry Shtokalo ; Denis Antonets ; Yuri Vyatkin ; Eleanor BattisonSeries Type : Expression profiling by genome tiling arrayOrganism : Homo sapiensWe found RNA markers common to both the discordant twin study and case-controlled subjects further narrowed the putative targets, some of which had been previously associated with ADHD at the DNA level. The potential role of several differentially expressed genes, including ABCB5, RGS2, GAK, GIT1 and 3 members of the galactose metabolism pathway (GALE, GALT, GALK1) are substantiated by prior associations to ADHD and by established mechanistic connections to molecular pathways relevant to ADHD and behavioral control.
In recognition of ADHD Awareness Month, NIMH will host a livestream event on October 21, 2020, from 1:00 - 1:30 p.m. ET, to discuss signs, symptoms, treatments, current research, and tips for helping children and adolescents manage ADHD during the pandemic.
We present data on predictors and mediators of such risk, highlighting a recent dual-process model involving trait impulsivity plus family- and peer-related contributors. We conclude with recommendations for assessment and preventive intervention. PMID: 33019955 [PubMed - as supplied by publisher]
Publication date: Available online 4 October 2020Source: Journal of Psychiatric ResearchAuthor(s): Qi Zhang, Xinzhen Chen, Shanyawen Li, Ting Yao, Jing Wu
This study assessed the impact of a recent (within past year) diagnosis of a mental disorder - including attention-deficit/hyperactivity disorder (ADHD), bipolar disorder, depression and schizophrenia - on the risk for COVID-19 infection and related mortality and hospitalization rates. We analyzed a nation-wide database of electronic health records of 61 million adult patients from 360 hospitals and 317,000 providers, across 50 states in the US, up to July 29, 2020. Patients with a recent diagnosis of a mental disorder had a significantly increased risk for COVID-19 infection, an effect strongest for depression (adjusted o...
TUESDAY, Oct. 6, 2020 -- Individuals with attention-deficit/hyperactivity disorder (ADHD) face higher financial distress and subsequent suicide risk, according to a study published online Sept. 30 in Science Advances. Theodore P. Beauchaine, Ph.D.,...
ConclusionsAdults with ADHD are less self-compassionate than adults without ADHD. This is partially explained by the higher level of criticism they perceive from others.
TUESDAY, Oct. 6, 2020 -- Girls who played after-school sports in elementary school seem to have fewer symptoms of attention-deficit/hyperactivity disorder (ADHD) once they reach middle school, a new study suggests. The research included both boys...
Conditions: Attention Deficit Hyperactivity Disorder; Attention Deficit Disorder; Attention Deficit Disorder With Hyperactivity Intervention: Drug: ADHD stimulants, for example, amphetamine, dexmethylphenidate, dextroamphetamine, methylphenidate Sponsor: Nemours Children's Clinic Recruiting
To examine the association of anemia with autism spectrum disorder (ASD), attention deficit/hyperactivity disorder (ADHD), and learning disability in US children.
Attention-deficit hyperactivity disorder (ADHD) is a common condition with neurodevelopmental origins that typically starts in early childhood and follows a persistent trait-like course. It is characterized by inattention, impulsivity and hyperactivity that persist over time and lead to clinical and psychosocial impairments. Emotional instability is a common feature and is sometimes the main presenting complaint. Neurodevelopmental and psychiatric co-morbidities are common. ADHD can be diagnosed and treated at all ages and persists into adulthood in around two-thirds of individuals.