Gut microbial short chain fatty acids are associated with pathological complete response (pCR) after neoadjuvant chemotherapy for breast cancer

Background: The composition and function of the gut microbiome may influence the activity of systemic anti-cancer therapies. However, it is not yet known whether and how the gut microbiome impacts on chemo-sensitivity in breast cancer. To address this we have investigated associations between short chain fatty acids (SCFAs), key functional metabolites of the gut microbiome, and pCR.

Source: European Journal of Cancer - September 30, 2020 Category: Cancer & Oncology Authors: K. Ross, R. Papadopoulou, B. Nichols, M. Macleod, J. Fraser, S. Barrett, J. Evans, K. Gerasimidis, I. Macpherson Tags: POSTER IN THE SPOTLIGHT: Poster in the Spotlight II Source Type: research