New germline RAD51D gene variant in the Mongol breast cancer patients

Background: In recent decades, breast cancer (BC) is the most common malignancy in the Russian Federation. The population is descended primarily from newcomers (Slavic ancestors) and indigenous population (Mongoloid race). Currently, nothing is known regarding the molecular factors associated with increased risk of hereditary BC in the indigenous population of Russia. BC prevention models for indigenous population have not been developed yet. Our aim was to evaluate the frequency of hereditary mutations of RAD50 and RAD51D genes in Mongol BC patients.
Source: European Journal of Cancer - Category: Cancer & Oncology Authors: Tags: POSTERS A: Genetics Source Type: research