Is sentinel lymph node biopsy necessary in the setting of microinvasive DCIS?

Background: Breast cancer treatment guidelines recommend the surgeon perform a sentinel lymph node biopsy (SLNB) for patients with ductal carcinoma in situ (DCIS) who have a high risk of invasive cancer or for whom a mastectomy is planned.
Source: European Journal of Cancer - Category: Cancer & Oncology Authors: Tags: POSTERS A: Optimal Diagnosis Source Type: research

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This study aimed to assess the long-term risk of ipsilateral subsequent in situ and invasive lesions after a diagnosis of primary DCIS and the association with initial DCIS treatment.
Source: European Journal of Cancer - Category: Cancer & Oncology Authors: Tags: PROFFERED PAPER SESSION: Are your breasts still at risk? Source Type: research
In the absence of clear interstitial invasion, encapsulated papillary carcinoma (EPC) of the breast may be attributed to an extremely good prognosis if handled similarly to ductal carcinoma in situ (DCIS) with suitable local treatment. Here, we report our experience with a case of EPC of the breast that presented with carcinomatous pleuritis and lymphangitis carcinomatosa postoperatively, which rapidly resulted in a poor outcome. A 67-year-old woman was diagnosed with DCIS of the left breast and underwent left partial mastectomy and sentinel lymph node biopsy. EPC was diagnosed because the pathological examination showed n...
Source: Case Reports in Oncology - Category: Cancer & Oncology Source Type: research
CONCLUSIONS: RBS rate can be reduced by shaving of cavity margins. Current standards for RBS should not be made more stringent due to the existence of non-actionable risk factors. The value of RBS as a quality indicator should be scrutinzed. PMID: 32841804 [PubMed - as supplied by publisher]
Source: Breast - Category: Cancer & Oncology Authors: Tags: Breast Source Type: research
Summary: The single biggest advancement in the aesthetic outcome of breast reconstruction following mastectomy has been the contribution of nipple-sparing mastectomy. By preserving the nipple–areolar complex, patients do not experience the same sense of loss that is observed in the setting of skin-sparing mastectomy. Despite this significant contribution, the challenge remains as to how surgeons can extend this option to larger-breasted patients or patients with significant breast ptosis. Several strategies have been described, including reduction mammoplasty before mastectomy, bipedicled simultaneous mastopexy wit...
Source: Plastic and Reconstructive Surgery – Global Open - Category: Cosmetic Surgery Tags: Breast: Ideas and Innovations Source Type: research
Conclusion: In every second patient who had first received a subcutaneous mastectomy, no tumor could be detected in the secondary operation despite a previous R1 status.
Source: In Vivo - Category: Research Authors: Tags: Clinical Studies Source Type: research
CONCLUSION: These findings support the use of prophylactic NSM in high-risk patients. The nipples could be preserved in the majority of patients, postoperative complication rates were low, and, with limited follow-up, there were no new breast cancers. PMID: 32432359 [PubMed - as supplied by publisher]
Source: The British Journal of Surgery - Category: Surgery Authors: Tags: Br J Surg Source Type: research
We present a rare case of Paget disease of the nipple without the typical characteristics, detected by simple nipple scraping technique. A 62-year-old woman presented with a small fissure on the left nipple with scant clear nippledischarge. There were no other changes to the nipple-areola complex. The mammography and ultrasound were unremarkable. However, nipplescraping provided the immediate cytological diagnosis of Paget disease. Breast MRI with core biopsy showed high grade ductal carcinoma in situwith suggestion of microinvasion, confirmed histologically after mastectomy. Nipple scraping is a simple and inexpensive tec...
Source: Dermatology Online Journal - Category: Dermatology Source Type: research
If you dread your annual mammogram, you’re not alone. For many women, this breast cancer screening examination can be painful, stressful, and just an overall hassle. You may wonder, are you old enough to give it up? If you’re over age 75, the answer is: maybe or maybe not. The fact is, breast cancer screening isn’t right for all older adults, but there’s no expert consensus on the right age to stop. This is mostly because scientific evidence in this area is lacking, says Dr. Kathryn Rexrode, associate professor of medicine at Harvard Medical School and chief of the Division of Women’s Health a...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Breast Cancer Healthy Aging Managing your health care Screening Women's Health Source Type: blogs
ConclusionsOur findings demonstrated efficacy and safety to perform NSM as prophylactic surgery with good oncological outcomes and low complication rates in a case series of Brazilian patients.
Source: Breast Cancer Research and Treatment - Category: Cancer & Oncology Source Type: research
CONCLUSIONS: MBC has increasing incidence. PR-negative status was associated with better overall survival and disease-free interval. Indications to radiotherapy and hormonal therapy need standardization and will benefit from prospective randomized control trials. PMID: 32147980 [PubMed - in process]
Source: The Israel Medical Association Journal - Category: General Medicine Tags: Isr Med Assoc J Source Type: research
More News: Breast Cancer | Breast Carcinoma | Cancer | Cancer & Oncology | Carcinoma | Carcinoma in Situ | DCIS (Ductal Carcinoma in Situ) | Ductal Carcinoma | Mastectomy