Topical Steroids as Adjunctive Therapy for Bacterial Keratitis: Evidence From a Retrospective Case Series of 313 Cases

This study included all patients with corneal scrape positive bacterial keratitis from January 2012 to December 2016 at the Sydney Eye Hospital, Sydney, Australia. Cases were identified from pathology results and hospital coding, and data collected from medical records. Results: A total of 313 eyes from 308 patients with a mean age of 51 years [interquartile range (IQR) 36–72] were included. Of these patients, 192 (61%) were treated with topical steroids. High-dose steroids were prescribed in 22 (11%) cases, regular-dose in 88 (46%), and low-dose in 82 (43%). The median time until the implementation of steroid use was 4 days (IQR 3–7). Patients prescribed with topical steroids had significantly longer healing times than the “no steroid” group (11 vs 6.5, P 
Source: Asia-Pacific Journal of Ophthalmology - Category: Opthalmology Tags: Original Study Source Type: research