DNA Damage and Cancer Immunotherapy: A STING in the Tale

The DNA damage response and the immune response provide two distinct barriers to tumorigenesis. Reisl änder et al. provide a comprehensive yet concise overview of the molecular interplay between these two anti-tumoral mechanisms. They further discuss how combinations of DNA damage response and immune checkpoint inhibitors are exploited for cancer therapy.

Source: Molecular Cell - August 16, 2020 Category: Cytology Authors: Timo Reisl änder, Florian J. Groelly, Madalena Tarsounas Tags: Review Source Type: research