Co-production of MCR-1 and NDM-1 by Escherichia coli sequence type 31 isolated from a newborn in Moscow, Russia

Polymyxins are among the few effective antibiotics against carbapenemase-producing bacteria. Convergence of polymyxin and carbapenem resistance due to the co-production of mcr-type enzymes and carbapenemases is a serious health threat. It is still relatively rare worldwide; however, in China the prevalence among patients in the clinical settings is increasing (Huang et al., 2020). Here, we report the co-production of mcr-1 and blaNDM-1 in a clinical Escherichia coli strain, ST31, outside mentioned region.

Source: International Journal of Infectious Diseases - September 22, 2020 Category: Infectious Diseases Authors: Ofeliia Sulian, Vladimir Ageevets, Irina Lazareva, Vladimir Gostev, Dmitry Popov, Tatiana Vostrikova, Alexander Sukhinin, Yuri Lobzin, Sergey Sidorenko Tags: Short Communication Source Type: research