Catalysts for RNA and DNA modification.

Catalysts for RNA and DNA modification.
Curr Opin Chem Biol. 2015 Jan 12;25C:110-114
Authors: Gillingham D, Shahid R
Abstract
To study DNAs and RNAs it is often necessary to chemically modify them. Nature's strategy for nucleic acid modification is to use selective catalysts, and chemists have begun to emulate this conceptual approach. In this review we present a summary of catalytic approaches toward the construction of modified RNAs and DNAs and outline our opinions on where new research is needed.
PMID: 25590584 [PubMed - as supplied by publisher]

Source: Current Opinion in Chemical Biology - January 12, 2015 Category: Biochemistry Authors: Gillingham D, Shahid R Tags: Curr Opin Chem Biol Source Type: research