Improving assessment and management of large non-pedunculated colorectal lesions in a Western center over 10 years: lessons learned and clinical impact

Conclusions ESD introduction and educational interventions allowed ER of more complex lesions, offset by increased complementary surgery for complications or intrinsic histological risk. Nevertheless, overall, they have reduced surgery demand and increased appropriateness and safety of LNPL management in our center. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text
Source: Endoscopy International Open - Category: Gastroenterology Authors: Tags: Original article Source Type: research

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Colorectal cancers are generally recognized to develop from polyps. This “adenoma-adenocarcinoma sequence” theory has been in the mainstream of development of colorectal neoplasms. However, another theory was revealed, which is considered to emerge directly from normal epithelium, not through the adenomatous stage. This theory is called “de novo” pathway. Now, it is possible to presume the histology of colorectal lesions using magnifying endoscopy (×100 folds, pit pattern classification) and endocytoscopy (×520 folds, EC classification).
Source: Gastrointestinal Endoscopy - Category: Gastroenterology Authors: Tags: Oral abstracts Source Type: research
This article provides information on assessment of the malignant potential of colorectal neoplasms. It takes a modern approach on the topic and integrates relevant information that aligns with the thinking process. The theory of thinking fast (reflex) and slow (rational) is used. By doing so, it is hoped that the learning process can be expedited and practiced immediately. The focus is on preresection assessment of nonpolypoid colorectal neoplasms. Assessment of polypoid, sessile-serrated adenoma/polyp, or inflammatory bowel disease dysplasia is briefly discussed. PMID: 31445686 [PubMed - in process]
Source: Clinical Colorectal Cancer - Category: Cancer & Oncology Authors: Tags: Gastrointest Endosc Clin N Am Source Type: research
Authors: Mansour-Ghanaei F, Varshi G, Joukar F, Ashoobi MT, Esmaeilpour J, Gharibpoor A, Daryakar A, Mansour-Ghanaei R, Balou HA, Saedi HS, Mavaddati S, Sepehrimanesh M Abstract Colon cancer is the most commonly diagnosed gastrointestinal cancers in developed countries with varied incidence and the onset age of disease worldwide. Overall, 161 participants who were under patronage of a local relief foundation and referred to the endoscopy ward of Razi Hospital affiliated to the Guilan University of Medical Sciences. These patients have been aged more than 50 or more than 40 years with history of colorectal cancer in...
Source: Journal of Medicine and Life - Category: General Medicine Tags: J Med Life Source Type: research
Purpose of review The detection of early colorectal cancer has improved notably since the introduction of bowel cancer screening programmes. This has created new challenges from endoscopic, histological and therapeutic perspectives. Here, we outline the limitations of current clinical practice and ways of implementing optical diagnosis to overcome these limitations. Recent findings Virtual chromoendoscopy without magnification for predicting or ruling out deep submucosal invasion is useful in real clinical practice for most lesions. However, magnifying virtual chromoendoscopy is needed to make an accurate diagnosis in...
Source: Current Opinion in Gastroenterology - Category: Gastroenterology Tags: ENDOSCOPY: Edited by Anthony N. Kalloo Source Type: research
Colorectal cancers have two development theories. One is “adenoma-adenocarcinoma sequence” theory. The other is considered to emerge directly from normal epithelium, not through the adenomatous stage. This theory is called “de novo” pathway. We aimed to investigate clinicopathological characteristics and long-term prognosis mainly on depressed-typ e colorectal carcinomas considered as “de novo” pathway.
Source: Gastrointestinal Endoscopy - Category: Gastroenterology Authors: Tags: Monday abstract Source Type: research
Colorectal cancers are generally recognized to develop from polyps. This “adenoma-adenocarcinoma sequence” theory has been in the mainstream of development of colorectal neoplasms. However, another theory was revealed, which is considered to emerge directly from normal epithelium, not through the adenomatous stage. This theory is called “de novo” pathway. It has become possible to presume the histology of colorectal lesions using magnifying endoscopy (×100 folds, pit pattern classification) and endocytoscopy (×520 folds, EC classification).
Source: Gastrointestinal Endoscopy - Category: Gastroenterology Authors: Tags: Tuesday abstract Source Type: research
By just engaging in the basic strategies in the Wheat Belly Total Health, Wheat Belly 10-Day Grain Detox, or Undoctored programs, many mild cases of small intestinal bacterial overgrowth, SIBO, reverse. These efforts thereby restore your ability to ingest prebiotic fibers without diarrhea, bloating, gas, abdominal discomfort, joint pain, and dark emotional feelings. Many people thereby are relieved of irritable bowel syndrome symptoms, fibromyalgia, or restless leg syndrome, or have greater power in reversing autoimmune conditions such as rheumatoid arthritis. Unfortunately, not everybody enjoys reversal of SIBO with our b...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: SIBO grain-free probiotic undoctored wheat belly Source Type: blogs
Colorectal cancers have two development theories in their development. One is “adenoma-adenocarcinoma sequence“ theory . The other type of cancers is considered to emerge directly from nomal epithelium , not through the adenomatous stage. This theory is called “de novo“ pathway in the present study. We investigated clinicopathological characteristics and long-term pro gnosis mainly on depressed-type colorectal carcinomas.
Source: Gastrointestinal Endoscopy - Category: Gastroenterology Authors: Tags: Monday abstract Source Type: research
Endosc Int Open 2017; 05: E1278-E1283 DOI: 10.1055/s-0043-117952 Background and aim The depth of tumor invasion is currently the only reliable predictive risk factor for lymph node metastasis before endoscopic treatment for colorectal cancer. However, the most important factor to predict lymph node metastasis has been suggested to be lymphovascular invasion rather than the depth of invasion. Thus, the aim of this study was to investigate the predictive relevance of lymphovascular invasion before endoscopic treatment. Methods The data on pT1 colorectal cancers that were resected endoscopically or surgically...
Source: Endoscopy International Open - Category: Gastroenterology Authors: Tags: Original article Source Type: research
Conclusions Most flat and depressed colorectal lesions were seen on non-magnifying NBI as brown lesions with the exception of some flat lesions that were indistinguishable in color from the adjacent normal mucosa. Some of these flat lesions were also found to have HGD or IC. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text
Source: Endoscopy International Open - Category: Gastroenterology Authors: Tags: Original article Source Type: research
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