Modulation of the inflammatory response to LPS by the recruitment and activation of brown and brite adipocytes in mice.

CONCLUSION: In conclusion, these results suggest an IL-1RA-mediated immunomodulatory activity of thermogenic adipocytes specifically in response to endotoxaemia. This encourages potential therapy involving brown and brite adipocytes for the treatment of obesity and associated metabolic diseases. PMID: 32954821 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32954821?dopt=Abstract

Source: Am J Physiol Endocri... - September 20, 2020 Category: Endocrinology Authors: Munro P, Dufies O, Rekima S, Loubat A, Duranton C, Boyer L, Pisani DF Tags: Am J Physiol Endocrinol Metab Source Type: research