Neuronal Reprogramming for Brain Repair: Challenges and Perspectives.
Neuronal Reprogramming for Brain Repair: Challenges and Perspectives.
Trends Mol Med. 2020 Sep 14;:
Authors: Bocchi R, Götz M
Abstract
Brain injuries and neurodegenerative diseases elicit neuronal loss that persists because the adult mammalian brain lacks robust regenerative abilities. Direct reprogramming of local glial cells into neurons is a promising strategy for neuronal replacement in vivo. We discuss recent advances and future challenges in this approach to brain repair.
PMID: 32943322 [PubMed - as supplied by publisher]
Source: Trends in Molecular Medicine - Category: Molecular Biology Authors: Bocchi R, Götz M Tags: Trends Mol Med Source Type: research