Antibodies to Rift valley fever virus in some wildlife and domestic animals in Bauchi State, Nigeria

Background: Rift valley fever (RVF) is an emerging zoonotic disease of public and animal health concern which is endemic in many countries in Sub-Saharan Africa. The virus is transmitted between wildlife, domestic animals and humans via arthropod vectors. Information on Rift valley fever virus in wild and domestic animals is limited in Bauchi State, Nigeria despite the availability of Yankari Game Reserve and Sumu Wildlife Park with wildlife, livestock and people competing for resources leading to porous frontiers and potential for transmission of zoonoses.
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: 0630 Source Type: research

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Comparative thermo-stability of two Rift Valley fever virus vaccine candidate CL13T with a recombinant arMP-12ΔNSm21/384. Bioinformation. 2020;16(7):547-554 Authors: Daouam S, Boumart Z, Elarkam A, Hamdi J, Tadlaoui KO, Ennaji MM, Harraka M Abstract Rift Valley fever (RVF) is a zoonotic, viral disease, transmitted by mosquitoes, characterized by high mortality rates in young animals. RVF is an endemic and enzootic disease in the Arabian Peninsula and Africa, causing public health and economic instability. Therefore, it is important to develop vaccines to minimize outbreaks and combat the disease...
Source: Bioinformation - Category: Bioinformatics Authors: Tags: Bioinformation Source Type: research
Abstract Primary pulmonary coccidioidomycosis (valley fever) is caused by inhaling airborne spores of the fungus Coccidioides immitis or Coccidioides posadasii. Residing in or traveling to areas endemic for Coccidioides is required for the diagnosis; no person-to-person or zoonotic contagion occurs. The incidence of coccidioidomycosis is increasing in endemic areas, and it has been identified as the cause of as many as 17% to 29% of all cases of community-acquired pneumonia in some regions. Obtaining a travel history is recommended when evaluating patients with community-acquired pneumonia. Diagnosis usually relie...
Source: American Family Physician - Category: Primary Care Authors: Tags: Am Fam Physician Source Type: research
This study showed an establishment of the first reverse genetics for AMTV, a lack of stability of AMTV NSs proteins in human cells, and an IFN-β gene antagonist function of AMTV NSs proteins in murine cells. The AMTV can be a nonpathogen ic surrogate model for studying phleboviruses including RVFV.
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
Conclusions/SignificanceThe high seroprevalence in all age groups and evidence of year-round viral circulation provide evidence for a hyperendemic situation in the study area. This is the first study to directly estimate infection rate of RVFV in livestock in an endemic area in the absence of reported outbreaks and provides the basis for further investigation of factors affecting viral circulation and mechanisms for virus survival during interepidemic periods.
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
Tiphany Chrun1,2*, Sandra Lacôte2, Céline Urien1, Charles-Adrien Richard1, Matthias Tenbusch3, Nicolas Aubrey4, Coralie Pulido5, Latifa Lakhdar5, Philippe Marianneau2* and Isabelle Schwartz-Cornil1* 1VIM-INRA-Université Paris-Saclay, Jouy-en-Josas, France2ANSES-Laboratoire de Lyon, Unité Virologie, Lyon, France3Institute of Clinical and Molecular Virology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, Medical Immunology Campus Erlangen, FAU Erlangen-Nürnberg, Erlangen, Germany4ISP, INRA, Université de Tours, UMR 1282 Team BioMAP, Nouzilly, F...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
In this study, we exposed apically well-differentiated human NECs cultured at the ALI to the related flaviviruses ZIKV, JEV, WNV, and Usutu virus (USUV). We selected these viruses due to the recent increasing evidences of potential threat to humans (Cadar et al., 2017; Simonin et al., 2018). We show that NECs are particularly susceptible to JEV and WNV infection and to other flaviviruses included in this study. Infection with each virus led to shedding of infectious virus particles through the apical and basolateral surfaces and triggered host mechanisms at the level of inflammatory and antiviral mediators. Given...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Abstract Rift Valley fever virus (RVFV) is an important mosquito-borne pathogen with devastating impacts on agriculture and public health. With outbreaks being reported beyond the continent of Africa to the Middle East, there is great concern that RVFV will continue to spread to non-endemic areas such as the Americas and Europe. There is a need for safe and high throughput serological assays for rapid detection of RVFV during outbreaks and for surveillance. We evaluated a multiplexing fluorescence microsphere immunoassay (FMIA) for the detection of IgG and IgM antibodies in ruminant sera against the RVFV nucleocap...
Source: Journal of Virological Methods - Category: Virology Authors: Tags: J Virol Methods Source Type: research
elmy Rift Valley fever (RVF) is an emerging transboundary, mosquito-borne, zoonotic viral disease caused high morbidity and mortality in both human and ruminant populations. It is considered an important threat to both agriculture and public health in African and the Middle Eastern countries including Egypt. Five major RVF epidemics have been reported in Egypt (1977, 1993, 1994, 1997, and 2003). The virus is transmitted in Egypt by different mosquito's genera such as Aedes, Culex, Anopheles, and Mansonia, leading to abortions in susceptible animal hosts especially sheep, goat, cattle, and buffaloes. Recurrent RVF ...
Source: Viruses - Category: Virology Authors: Tags: Review Source Type: research
Abstract Rift Valley fever virus (RVFV), a mosquito-borne, zoonotic pathogen, is endemic to sub-Saharan Africa and has spread beyond the continent to the Arabian Peninsula. The high likelihood of RVFV's spread to other non-endemic countries spurs the need for development and implementation of rapid diagnostic tests and surveillance programs. In this preliminary evaluation, we assessed the diagnostic accuracy and precision of a recombinant RVFV nucleoprotein based competitive ELISA (cELISA) assay to detect RVFV antibodies compared to a plaque reduction neutralization test (PRNT80), using sera of cattle and sheep th...
Source: Journal of Virological Methods - Category: Virology Authors: Tags: J Virol Methods Source Type: research
Rift Valley fever (RVF) is classified as viral hemorrhagic fever and is endemic in East and West Africa. RVF is caused by an arthropod borne virus (RVFV); the disease is zoonotic and affects human, animal heal...
Source: BMC Veterinary Research - Category: Veterinary Research Authors: Tags: Research article Source Type: research
More News: African Health | Coccidioidomycosis (Valley Fever) | Endemics | Infectious Diseases | Nigeria Health | Zoonoses