Human papillomavirus 16 (HPV 16) E6 but not E7 inhibits the antitumor activity of LKB1 in lung cancer cells by downregulating the expression of KIF7
ConclusionsHere, we demonstrated for the first time that E6 but not E7 inhibits the antitumor activity of LKB1 in lung cancer cells by downregulating the expression of KIF7. Our findings provide new evidence to support the important role of KIF7 in the pathogenesis of lung cancer and suggests new therapeutic targets.
Source: Thoracic Cancer - Category: Cancer & Oncology Authors: Yue Hu,
Ming ‐Zhe Wu,
Na‐Jin Gu,
Hong‐Tao Xu,
Qing‐Chang Li,
Guang‐Ping Wu Tags: ORIGINAL ARTICLE Source Type: research
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