Recombinant Forms CRF109_0107 in China

Inter-subtype recombinants play an increasingly central role in the complex and dynamic HIV/AIDS epidemic. At present, 106 Circulate recombinant forms (CRFs) have been identified worldwide. In 2000, CRF07_BC and CRF08_BC were first reported in China, and novel CRFs identified in China has soared since 2013. Inter-subtype recombinant viruses, especially CRF01_AE and CRF07_BC, have become the predominant strains of the HIV-1 epidemic in China1. The double infection between CRFs established more optimal conditions for the second-generation recombination2, and many second-generation recombinants were represented by the recombination of CRF01_AE and CRF07_BC fragments, such as CRF79_01073, CRF80_01074, and CRF102_01075.

Source: Journal of Infection - September 14, 2020 Category: Infectious Diseases Authors: Xiaorui Wang, Jin Zhao, Xi Li, Hanping Li, Yu Zhang, Yongjian Liu, Lin Chen, Chenli Zheng, Lei Jia, Jingwan Han, Tianyi Li, Xiaolin Wang, Jingyun Li, Hongling Wen, Lin Li Source Type: research