Identification of candidate mediators of chemoresponse in breast cancer through therapy-driven selection of somatic variants

ConclusionsGenomic analysis of paired pre- and post-therapy samples resulting from neoadjuvant therapy provides a powerful method for identification of mediators of response. Genes we identified should be assessed as predictive markers or targets in chemo-sensitization.
Source: Breast Cancer Research and Treatment - Category: Cancer & Oncology Source Type: research