The effect of diabetic ketoacidosis (DKA) and its treatment on clot microstructure: Are  they thrombogenic?

CONCLUSIONS: DKA patients at presentation have a densely organising less permeable thrombogenic clot microstructure as evidenced by high df. These structural changes are due to a combination of dehydration and a profound metabolic acidosis, which was reversed with treatment. These changes were not mirrored in standard clinical markers of thromboge-nicity.
PMID: 32925001 [PubMed - as supplied by publisher]

Source: Clinical Hemorheology and Microcirculation - September 9, 2020 Category: Hematology Authors: Pillai S, Davies G, Lawrence MJ, Whitley J, Stephens JW, Williams PR, Morris K, Evans PA Tags: Clin Hemorheol Microcirc Source Type: research