Proton pump inhibitors vs. histamine-2 receptor antagonists likely increase mortality in critical care: an updated meta-analysis
Upper gastrointestinal bleeding is common among the critically ill. Recently, the Proton Pump Inhibitors (PPIs) vs. Histamine-2 Receptor Blockers (H2RAs) for Ulcer Prophylaxis Therapy in the Intensive Care Unit (PEPTIC) trial suggested PPIs might increase mortality. We performed an updated meta-analysis to further inform discussion.
Source: The American Journal of Medicine - Category: General Medicine Authors: Todd C. Lee, Marnie Goodwin Wilson, Alexander Lawandi, Emily G. McDonald Tags: Brief Observation Source Type: research
More News: Bleeding | Gastroenterology | General Medicine | Intensive Care | Legislation | Peptic Ulcer | Proton Pump Inhibitors PPIs