Multimodal CEA-targeted image-guided colorectal cancer surgery using 111In-labeled SGM-101.

CONCLUSIONS: [111In]In-DTPA-SGM-101 showed specific accumulation in colorectal tumors, and enabled micro-SPECT/CT imaging and fluorescence-guided tumor resection. Thus, [111In]In-DTPA-SGM-101 could be a valuable tool for preoperative SPECT/CT imaging and intraoperative radioguided localization and fluorescence-guided resection of colorectal cancer. PMID: 32900795 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32900795?dopt=Abstract

Source: Clinical Cancer Research - September 7, 2020 Category: Cancer & Oncology Authors: de Gooyer JM, Elekonawo FMK, Bos DL, van der Post RS, Pèlegrin A, Framery B, Cailler F, Vahrmeijer AL, de Wilt JHW, Rijpkema M Tags: Clin Cancer Res Source Type: research