60. Beta-lactam antibiotic surgical prophylaxis is safe in patients with self-reported penicillin allergies: a cohort study of lumbar spine surgery patients

The use of first-generation cephalosporins for perioperative antibiotic prophylaxis in elective spine surgery is strongly recommended. Patients with self-reported penicillin (PCN) allergies are often administered suboptimal alternative antibiotics given the concern for distant cross-reactivity. The reliability of patient-reported PCN allergies has been disputed and is poorly understood.
Source: The Spine Journal - Category: Orthopaedics Authors: Source Type: research