Patterns of cutaneous immune-related adverse events in adults and children with advanced sarcoma: A retrospective cohort study.

Patterns of cutaneous immune-related adverse events in adults and children with advanced sarcoma: A retrospective cohort study.
Br J Dermatol. 2020 Sep 07;:
Authors: Thompson LL, Chang MS, McCormack L, Polyakov N, Yoon J, Song H, Huang JT, Chen ST
Abstract
Immune checkpoint inhibitors (ICIs) have improved survival for multiple malignancies in adults and children.1,2 However, their benefits are tempered by a range of serious immune-related adverse events (irAEs). 1,2 Among these, cutaneous irAEs (cirAEs) represent one of the most common subtypes, impacting approximately one-third of adult patients receiving ICIs.1,3 The patterns and significance of cirAEs in children remain unclear, largely because these reactions have not been evaluated in detail.
PMID: 32894776 [PubMed - as supplied by publisher]

Source: The British Journal of Dermatology - September 6, 2020 Category: Dermatology Authors: Thompson LL, Chang MS, McCormack L, Polyakov N, Yoon J, Song H, Huang JT, Chen ST Tags: Br J Dermatol Source Type: research