Low levels of CD72 and CD100 expression on circulating lymphocytes in immunosuppressive phase of sepsis is associated with mortality in septic patients

ConclusionsOur study demonstrated that the decrease of the levels of CD72 and CD100 expression on circulating lymphocytes after 3 –4 days of sepsis had a close correlation of the 28-day mortality of septic patients. Thus, CD72 and CD100 are promising biomarkers for assessing the prognosis of patients with sepsis.Trial registrationPeripheral blood lymphocytes analysis detects CD72 and CD100 alteration in trauma patients; ChiCTR1900026367; Registered 4 October 2019;http://www.chictr.org.cn.
Source: Journal of Intensive Care - Category: Intensive Care Source Type: research