Response to: Loutradis, et al. Longer dialysis sessions improve cardiac systolic function by reducing myocardial stunning

We are grateful for the chance to correspond with Loutradis et al. who reasonably suggest that reduced volume overload may drive improvement in end-diastolic volume. In response to this, we have conducted a further analysis of the ACTIVE Dialysis trial participants to determine if a change in body weight was associated with change in end-diastolic volume, or modified the relationship between this parameter and allocation to extended hours dialysis. As described in detail elsewhere,12 95 members of a larger cohort of hemodialysis recipients randomised to extended ( ≥24 hours per week) or standard (12-18 hours per week) hemodialysis for 12 months had cardiac magnetic resonance imaging performed at baseline and study end.

Source: Journal of Cardiac Failure - September 1, 2020 Category: Cardiology Authors: Brendan Smyth, Christopher T Chan, Stuart M Grieve, Rajesh Puranik, Li Zuo, Daqing Hong, Nicholas A Gray, Janak R de Zoysa, Anish Scaria, Martin Gallagher, Vlado Perkovic, Meg Jardine Source Type: research