A textbook example of bias in Disorders/Differences of Sex Development (DSD) outcome research. A commentary to: “Congenital adrenal hyperplasia: Does repair after two years of age have a worse outcome?”

With interest I have read the article by Elsayed and colleagues on the outcomes of genital surgery in girls with Congenital Adrenal Hyperplasia (CAH) before versus after the age of two [1]. The authors validly mention the unsettled debate on performing genital surgeries on girls with virilized genitalia before the age of consent. In their study the authors, rather than providing conclusive arguments, exhibit the many pitfalls and biases of studying the outcomes of those that received this treatment.
Source: Journal of Pediatric Urology - Category: Urology & Nephrology Authors: Tags: Letter to the Editor Source Type: research