The Efficacy of Mycoplasma gallisepticum K-strain live vaccine in broiler and layer chickens.

The Efficacy of Mycoplasma gallisepticum K-strain live vaccine in broiler and layer chickens. Avian Pathol. 2015 Jan 9;:1-27 Authors: Ferguson-Noel NM, Williams SM Abstract The efficacy of a live Mycoplasma gallisepticum (MG) vaccine candidate (K-strain) was compared to commercially available vaccines in broiler-type chickens (Trial 1) and layer-type chickens (Trial 2). In Trial 1, 3-week-old broiler-type chickens were vaccinated via aerosol with K-strain or an F-strain vaccine. The vaccinated chickens and 10 non-vaccinated controls were subsequently challenged with virulent R-strain via aerosol at 6 weeks post vaccination; both K-strain and F-strain vaccination resulted in significant protection from air sac and tracheal lesions, as well as R-strain colonization (P < 0.05). In Trial 2, commercial layer-type chickens were vaccinated with ts-11 (via eye drop) or K-strain (via aerosol) at 12 weeks of age. At 25 weeks of age these birds were challenged with R-strain via aerosol. The ts-11 and K-strain vaccinated groups both had significantly lower air sac lesion scores and a lower prevalence of ovarian regression after challenge as compared to non-vaccinated chickens (P < 0.05). K-strain vaccination also prevented significant tracheal lesions and R-strain colonization (P < 0.05). K-strain shows great potential as a highly efficacious live MG vaccine in broiler and layer-type chickens for protection of the respiratory and reprod...
Source: Avian Pathology - Category: Pathology Authors: Tags: Avian Pathol Source Type: research