Sorting and gene mutation verification of circulating tumor cells of lung cancer with epidermal growth factor receptor peptide lipid magnetic spheres

ConclusionsEG ‐P‐LMB can effectively capture CTCs in the peripheral blood of patients with lung cancer. CTC detection can accurately identify mutations in theEGFR gene and improve the ability to obtain tumor tissue in clinical practice.Key pointsSignificant findings of the studyEG ‐P‐LMB can effectively capture CTCs in the peripheral blood of patients with lung cancer. CTC detection can accurately identify mutations in theEGFR gene and improve the ability to obtain tumor tissue in clinical practice.What this study addsThis study added EGFR peptide lipid magnetic spheres to capture CTCs in the blood. Genetic testing was performed and compared with tissues. It solves the problem of clinically difficult tumor tissue sampling.

Source: Thoracic Cancer - August 26, 2020 Category: Cancer & Oncology Authors: Sheng ‐guang Wang, Bin Zhang, Chen‐guang Li, Jian‐quan Zhu, Bing‐sheng Sun, Chang‐li Wang Tags: ORIGINAL ARTICLE Source Type: research