Meibomian Gland Dysfunction and Its Association With Ocular Discomfort in Patients With Ocular Prosthesis

Objective:
To investigate the effects of ocular prosthesis on meibomian glands and also to identify the role of meibomian gland dysfunction (MGD) on ocular discomfort in prosthetic eyes.
Methods:
This prospective study included 55 patients who had been wearing unilateral ocular prosthesis for more than 1 year. A 15-item questionnaire regarding MGD-related ocular symptoms was administered to all patients. Both prosthetic eyes and paired normal eyes were evaluated with slit-lamp, noncontact meibography and spectral optical coherence tomography. A multiple linear regression model was applied to evaluate factors on ocular symptom scores.
Results:
The ocular symptom scores, meibography scores, meibomian gland loss, and lid margin abnormality scores of prosthetic eyes were significantly higher than those of normal eyes (P

Source: Eye and Contact Lens: Science and Clinical Practice - August 25, 2020 Category: Opthalmology Tags: Article Source Type: research