Low risk of serological cross-reactivity between dengue and COVID-19.

Low risk of serological cross-reactivity between dengue and COVID-19.
Mem Inst Oswaldo Cruz. 2020;115:e200225
Authors: Spinicci M, Bartoloni A, Mantella A, Zammarchi L, Rossolini GM, Antonelli A
Abstract
In the near future, the overlap of Coronavirus disease 2019 (COVID-19) and dengue epidemics is a concrete threat in tropical regions. Co-epidemics of COVID-19 and dengue could be an overwhelming challenge for health systems in low- and middle-income countries. In this work, we investigated potential serological cross-reactions between COVID-19 and dengue patients. Among 32 COVID-19 positive sera, no positive Dengue virus (DENV) IgG/IgM results were observed. On the other hand, one false-positive result was observed among 44 DENV-positive sera tested for COVID-19 antibodies with each of the two rapid tests used. Further data on accuracy of COVID-19 diagnostic test are urgently warranted.
PMID: 32813814 [PubMed - as supplied by publisher]

Source: Memorias do Instituto Oswaldo Cruz - August 20, 2020 Category: Infectious Diseases Authors: Spinicci M, Bartoloni A, Mantella A, Zammarchi L, Rossolini GM, Antonelli A Tags: Mem Inst Oswaldo Cruz Source Type: research