Two-stage Bayesian hierarchical modeling for blinded and unblinded safety monitoring in randomized clinical trials

Monitoring and reporting of drug safety during a clinical trial is essential to its success. More recent attention to drug safety has encouraged statistical methods development for monitoring and detecting pot...

Source: BMC Medical Research Methodology - August 17, 2020 Category: Research Authors: Junhao Liu, Jo Wick, Renee ’ H. Martin, Caitlyn Meinzer, Dooti Roy and Byron Gajewski Tags: Research article Source Type: research