STAT6 Variants Associate With Relapse of Eosinophilic Esophagitis in Patients Receiving Long-Term Proton Pump Inhibitor Therapy

Variants in STAT6 associate with a poor initial response, based on histologic features, to proton pump inhibitor (PPI) therapy in pediatric patients with eosinophilic esophagitis (EoE). We investigated whether these genetic variants associate with a poor long-term response in children with EoE who initially responded to PPI therapy.

Source: Clinical Gastroenterology and Hepatology - August 12, 2020 Category: Gastroenterology Authors: Edward B. Mougey, Vivian Nguyen, Carolina Guti érrez-Junquera, Sonia Fernández-Fernández, Maria Luz Cilleruelo, Ana Rayo, Belén Borrell, Enriqueta Román, Carmen González-Lois, Montserrat Chao, Hadeel Al-Atrash, James P. Franciosi Source Type: research