Clinical Metagenomic Sequencing for etiological diagnosis in pulmonary tuberculosis suspects

Tuberculosis (TB), which is caused by the bacillus Mycobacterium tuberculosis (MTB), remains a leading cause of death from infectious disease. According to the 2019 World Health Organization global report, TB was one of the top 10 causes of death worldwide, ranking above acquired immune deficiency syndrome. There were an estimated 10.0 million newly diagnosed TB cases worldwide in 2018, with a high incidence and mortality in developing countries1, 2. Although effective treatment has been available for decades, the difficulty faced by physicians has been the issue of rapid and reliable diagnosis.

Source: Journal of Infection - August 3, 2020 Category: Infectious Diseases Authors: Cui-Lin Shi, Peng Han, Pei-Jun Tang, Meng-Meng Chen, Zhi-Jian Ye, Mei-Ying Wu, Jie Shen, Hai-Yan Wu, Zhu-Qing Tan, Xin Yu, Guan-Hua Rao, Jian-Ping Zhang Source Type: research