Carbetocin compared with oxytocin in non-elective Cesarean delivery: a systematic review, meta-analysis, and trial sequential analysis of randomized-controlled trials

ConclusionsCarbetocin reduces the need for additional uterotonics in non-elective CD compared with oxytocin. TSA confirmed that this analysis was appropriately powered to detect the pooled estimated effect. Further trials utilizing consistent core outcomes are needed to determine an effect on PPH.Trial registrationPROSPERO CRD42019147256, registered 13 September 2019.
Source: Canadian Journal of Anesthesia - Category: Anesthesiology Source Type: research