Different Expression of Duodenal Genes Related to Insulin Resistance Between Nonobese Women and Those with Severe Obesity.

CONCLUSIONS: Independent of BMI, higher insulin resistance was associated with a downregulation of duodenal DEGs mainly related to the immune system, inflammation, and xenobiotic metabolism. Also, intestinal lipoprotein metabolism may have a certain relevance in the regulation of insulin resistance in nonobese women. PMID: 32729246 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32729246?dopt=Abstract

Source: Obesity - July 28, 2020 Category: Eating Disorders & Weight Management Authors: Ho-Plagaro A, Santiago-Fernandez C, Rodríguez-Díaz C, Lopez-Gómez C, Garcia-Serrano S, Rodríguez-Pacheco F, Valdes S, Rodríguez-Cañete A, Alcaín-Martínez G, Ruiz-Santana N, Vázquez-Pedreño L, García-Fuentes E Tags: Obesity (Silver Spring) Source Type: research