No Evidence of Altered Reactivity to Experimentally Induced Pain Among Regular Cannabis Users

This study explored differences in measures of pain intensity and tolerance. The authors hypothesized that individuals who report frequent CU would demonstrate greater experimental pain sensitivity. Materials and Methods: Frequent cannabis users (≥3× per week; n=40) and nonusers (n=40) were compared on pain sensitivity, pain tolerance, and pain intensity in response to a cold-pressor task. Group differences were examined. Results: Frequent CU was not associated with hyperalgesia as cannabis users and nonusers did not exhibit differences on measures of pain tolerance (t(78)=−0.05; P=0.96), sensitivity (t(78)=−0.83; P=0.41), or intensity (t(78)=0.36; P=0.72). Discussion: Frequent cannabis users did not demonstrate hyperalgesia. This finding should help to inform evaluations of the relative harms and benefits of cannabis analgesic therapies.
Source: The Clinical Journal of Pain - Category: Anesthesiology Tags: Original Articles Source Type: research