Central sensitization of nociceptive pathways demonstrated by robot-controlled pinprick-evoked brain potentials.

CONCLUSIONS: This study shows increased PEPs after HFS when they are elicited by a robot-controlled mechanical pinprick stimulator and participants are engaged in a stimulus evaluation task during pinprick stimulation.
SIGNIFICANCE: This is the first study that shows a significant increase of both PEP peaks, and therefore, it provides a preferred setup for assessing the function of mechanical nociceptive pathways in the context of central sensitization.
PMID: 32709556 [PubMed - as supplied by publisher]

Source: Clinical Neurophysiology - July 8, 2020 Category: Neurology Authors: van den Broeke EN, de Hemptinne P, Mercken M, Torta DM, Lambert J, Mouraux A Tags: Clin Neurophysiol Source Type: research