Mesenchymal stem cells ameliorate partial bladder outlet obstruction-induced epithelialmesenchymal transition type II independent of mast cell recruitment and degranulation.

CONCLUSIONS: Our results demonstrate the involvement of EMT type II in the pathophysiology of pBOO and confirm its mitigation with MSC treatment independent of mast cells response. The observations provide insight into the mechanism of action and have therapeutic ramifications. PMID: 32701447 [PubMed - as supplied by publisher]
Source: Canadian Urological Association Journal - Category: Urology & Nephrology Authors: Tags: Can Urol Assoc J Source Type: research