Linking cortical and behavioural inhibition: Testing the parameter specificity of a transcranial magnetic stimulation protocol

Across a series of studies, our lab has shown that the efficiency of action stopping is associated with the strength of GABAA-mediated short-intracortical inhibition (SICI) as measured using transcranial magnetic stimulation (TMS). However, these studies used fixed TMS parameters, which may not optimally probe GABAA receptor activity for each individual. In the present study, we measured the relationship between stopping efficiency and SICI using a range of TMS parameters. Participants completed a right-hand unimanual stop signal task to obtain a measure of stopping efficiency.

Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - July 22, 2020 Category: Neurology Authors: Dominic M.D. Tran, Nahian S. Chowdhury, Nicolas A. McNair, Justin A. Harris, Evan J. Livesey Source Type: research