Prevalence of natural and acquired antibodies to amustaline/glutathione pathogen reduced red blood cells.

CONCLUSION: Standardized RRC screening panels are sensitive for the detection of natural and acquired S-303-specific antibodies. Natural low titer antibodies to amustaline/GSH RBC are present in 0.15% of naïve patients. The clinical relevance of these antibodies appears minimal but is under further investigation.
PMID: 32692456 [PubMed - as supplied by publisher]

Source: Transfusion - July 20, 2020 Category: Hematology Authors: Geisen C, North A, Becker L, Brixner V, von Goetz M, Corash L, Benjamin RJ, Mufti N, Seifried E Tags: Transfusion Source Type: research