18F-sodium fluoride bone deposition quantitation with PET in Mice: Variation with age, sex, and circadian rhythm.

CONCLUSION:  Circadian rhythm had a significant impact on uptake only in F of 3 and 6 months. Regarding sex, F showed generally higher uptake rates than M. The highest uptake values were observed during bone growth at age 1 month in both sexes, a second uptake peak occurred in elderly F. Designing future bone uptake studies with M, attention must be paid to age only, while in F circadian rhythm and age must be taken into account.
PMID: 32674198 [PubMed - as supplied by publisher]

Source: Nuklearmedizin - July 15, 2020 Category: Radiology Authors: Dorau-Rutke V, Huang K, Lukas M, Schulze MO, Rosner C, Gregor-Mamoudou B, Steffen IG, Brenner W, Beindorff N Tags: Nuklearmedizin Source Type: research