Healthy offspring from testicular tissue plantation in mice: Retinoic acid key

(Shinshu University) Germ cell depletion in recipient testis has adverse effects on spermatogenesis in orthotopically transplanted testis pieces via retinoic acid insufficiency. Repetitive RA administration significantly improved donor spermatogenesis to produce healthy offspring.
Source: EurekAlert! - Social and Behavioral Science - Category: International Medicine & Public Health Source Type: news