Brainstem iron overload and injury in a rat model of brainstem hemorrhage

Brainstem hemorrhage (BSH) is the most devastating subtype of intracerebral hemorrhage (ICH) with the highest mortality ranging from 56 % to 61.2 %. However, there is no effective medical or surgical therapy to improve its outcomes in clinic to date due to lack of understanding of its injury mechanisms. Herein, we explored the brainstem iron overload and injury in a rat model of BSH.

Source: Journal of Stroke and Cerebrovascular Diseases - July 15, 2020 Category: Neurology Authors: Xi Guo, Lu Ma, Hao Li, Xin Qi, Yang Wei, Zhongxin Duan, Jiake Xu, Chengwei Wang, Chao You, Meng Tian Source Type: research