Should patients with symptomatic cholelithiasis before 30 years of age be tested for ABCB4 gene mutations?

CONCLUSION: Our results suggest that LPAC should be systematically suspected and investigated in patients with symptomatic cholelithiasis before age of thirty, but genetic testing should only be attempted in patients complying with the more stringent LPAC criteria. PMID: 32650689 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32650689?dopt=Abstract

Source: Scandinavian Journal of Gastroenterology - July 12, 2020 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research