Activation, Deficiency, and Reduced IFN- γ Production of Mucosal-Associated Invariant T Cells in Patients with Inflammatory Bowel Disease

This study demonstrates that circula ting MAIT cells are activated and numerically and functionally deficient in IBD patients. Furthermore, activated MAIT cells have the potential to migrate to inflamed tissues. These findings suggest an important role of MAIT cells in mucosal immunity in IBD.J Innate Immun
Source: Journal of Innate Immunity - Category: Allergy & Immunology Source Type: research