Survival of Melancholia: a Retrospective Study of Patients with Depressive Disorders.

Survival of Melancholia: a Retrospective Study of Patients with Depressive Disorders. East Asian Arch Psychiatry. 2020 Jun;30(2):39-43 Authors: Gupta R, Mirza T, Majeed MH, Seemüller F, Moeller HJ Abstract BACKGROUND: The DSM-IV and the DSM-5 eliminated the importance of the syndromal identity of melancholic depression in favour of a dimensional model within the domain of major depressive disorders. Melancholic depression was excluded from DSM as a distinct disorder owing to the impact of ageing, genetics, and course of illness. We challenge these assertions using retrospective data collected from patients with depression. METHOD: Electronic medical records of 1073 patients with depressive-spectrum disorders in 12 centres across Germany spanning from January 2010 to June 2013 were retrospectively reviewed. The diagnosis of melancholia was made using the Hamilton Depression Rating Scale 21 items (HAMD-21). Patients were followed up every 2 weeks and yearly until discharge from inpatient units. The final dataset consisted of 1014 patients; each had received a minimum of two complete observations. RESULTS: At baseline, patients with melancholic depression had higher HAMD-21 score than did patients with non-melancholic depression (32.6 vs 23.13, p
Source: East Asian Archives of Psychiatry - Category: Psychiatry Tags: East Asian Arch Psychiatry Source Type: research

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