Secondary analysis of RTOG 0247 demonstrates favorable OS rates for rectal cancer patients

Locally advanced rectal cancer patients who receive preoperative radiation therapy with either irinotecan plus capecitabine or oxaliplatin plus capecitabine have a four-year overall survival rate of 85 percent and 75 percent, respectively, according to a study.
Source: ScienceDaily Headlines - Category: Science Source Type: news

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Authors: Okimoto T, Tsubata Y, Hotta T, Hamaguchi M, Nakao M, Hamaguchi SI, Hamada A, Isobe T Abstract The central nervous system is a common site of relapse in patients receiving crizotinib, which is presumed to be associated with the low concentration of crizotinib in the cerebrospinal fluid (CSF). Our patient received surgical treatment for anaplastic lymphoma kinase-positive stage IIA lung adenocarcinoma. His cancer recurred with brain metastases and carcinomatous meningitis. We started whole-brain radiation therapy (WBRT) and subsequently administered crizotinib. The concentration of crizotinib on day 15 in th...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
ConclusionsGenerally, superior vena cava syndrome is the result of extrinsic compression of the superior vena cava by tumor. Our patient ’s case represents the development of superior vena cava syndrome after an excellent response of tumor with near-complete tumor response. We suspect chemoradiation therapy as a potential etiology for the precipitation of the superior vena cava syndrome, which is currently not well reported in the medical literature.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
Condition:   Uveal Melanoma Interventions:   Radiation: Stereotactic Body Radiation Therapy;   Biological: Ziv-Aflibercept Sponsors:   Sidney Kimmel Cancer Center at Thomas Jefferson University;   Regeneron Pharmaceuticals Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Researchers from China have developed a radiomics model that can determine...Read more on AuntMinnie.comRelated Reading: Radiomics helps distinguish lung cancer nodules on CT AIUM: Can deep learning classify liver fibrosis on US? AI, radiomics help distinguish lung nodules on CT scans MRI, radiomics help diagnose, discern ADHD subtypes AAPM: Radiomics helps fine-tune radiation therapy dose
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Abstract Over the past decades, effective cancer therapies have resulted in a significant improvement in the survival rates for a number of cancers and an increase in the number of cancer survivors. Radiation therapy is widely used in the treatment of cancer, and it can induce various cardiotoxicities that differ considerably from chemotherapy-induced cardiotoxicity. They occur primarily as late radiation-induced complications, several years from the end of anticancer treatment and present as coronary artery disease, heart failure, pericardial disease, valvular heart disease and arrhythmias. Patients who recovered...
Source: Cardiology Journal - Category: Cardiology Authors: Tags: Cardiol J Source Type: research
Pacey Medtech, based in Vancouver, Canada, has developed the Pacey Cuff, a urethral control device for urinary incontinence in men, post-prostate cancer treatment. Treating prostate cancer can sometimes lead to urinary incontinence, which can have si...
Source: Medgadget - Category: Medical Devices Authors: Tags: Exclusive Rehab Urology Source Type: blogs
Radiation therapy software developer RaySearch Laboratories plans to exhibit...Read more on AuntMinnie.comRelated Reading: RaySearch signs Canadian cancer center RaySearch, Canon sign collaboration pact RaySearch signs Swedish Cancer Institute RaySearch to highlight software upgrades at AAPM RaySearch wins Canadian installation
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Noncolorectal gastrointestinal (GI) malignancies are among the most frequently diagnosed cancers. Despite the undeniable progress in systemic treatments in recent decades, further improvements using cytotoxic chemotherapy seem unlikely. In this setting, recent discoveries regarding the mechanism underlying immune evasion have prompted the study of molecules capable of inducing strong antitumor responses. Thus, according to early data, immunotherapy is a very promising tool for the treatment of patients with GI malignancies. Noncolorectal GI cancers are a major public health problem worldwide. Traditional treatment options,...
Source: Clinics - Category: General Medicine Source Type: research
A 150-year-old drug used to increase blood flow throughout the body appears to improve cancer treatment radiation by making tumors more sensitive to the therapy.
Source: Health News - UPI.com - Category: Consumer Health News Source Type: news
CONCLUSIONSBased on the current Medicare Physician Fee Schedule, HRS is cost-effective at a willingness to pay threshold of $100,000. These results contain substantial uncertainty, suggesting more evidence is needed to refine future decision making.
Source: Practical Radiation Oncology - Category: Cancer & Oncology Source Type: research
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