Single-cell Transcriptome Profiling reveals Dermal and Epithelial cell fate decisions during Embryonic Hair Follicle Development
Conclusions: Our findings here provide a molecular landscape during hair follicle epithelium/dermal cell lineage fate decisions, and recapitulate the sequential activation of core regulatory transcriptional factors (TFs) in different cell populations during hair follicle morphogenesis. More importantly, our study here represents a valuable resource for understanding the molecular pathways involved during hair follicle de novo morphogenesis, which will have implications for future hair loss treatments.
Source: Theranostics - Category: Molecular Biology Authors: Wei Ge, Shao-Jing Tan, Shan-He Wang, Lan Li, Xiao-Feng Sun, Wei Shen, Xin Wang Tags: Research Paper Source Type: research