Development and efficacy of a nested real-time quantitative polymerase chain reaction to identify the cytochrome c oxidase subunit 1 gene of Sarcoptes scabiei var. hominis for diagnosis and monitoring of ordinary scabies.

Development and efficacy of a nested real-time quantitative polymerase chain reaction to identify the cytochrome c oxidase subunit 1 gene of Sarcoptes scabiei var. hominis for diagnosis and monitoring of ordinary scabies. Br J Dermatol. 2020 Jun 28;: Authors: Kim JK, Chun EJ, Yang SY, Kim KS, Kim SS, Kim CW Abstract Dear Editor, Scabies infestation is increasingly a public health concern, even in high-income countries. The disability-adjusted life-years (DALYs) globally was estimated to be 71·11 (95% CI 39·77-116·03) per 100,000 people based on the results of a cross-sectional analysis from the Global Burden of Disease Study 20158 . The gold standard for scabies diagnosis is microscopic examination of skin scrapings in mineral oil, but the sensitivity of this technique is low3 ; as a result, scabies infestation cannot be ruled out even when this test is negative. PMID: 32594512 [PubMed - as supplied by publisher]
Source: The British Journal of Dermatology - Category: Dermatology Authors: Tags: Br J Dermatol Source Type: research